Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831822 | 1.00 | TRPV1 (0.51) | TRPV1KDRMEN1KMT2AMAPT | |
| SCHEMBL23831756 | 0.93 | KDR (0.45) | TRPV1KDRMEN1KMT2AMAPT | |
| SCHEMBL30105305 | 0.93 | KDR (0.45) | TRPV1KDRMEN1KMT2AMAPT | |
| SCHEMBL30104981 | 0.90 | TRPV1 (0.53) | TRPV1KDRMEN1KMT2AMAPT | |
| SCHEMBL23831651 | 0.90 | TRPV1 (0.53) | TRPV1KDRMEN1KMT2AMAPT | |
| SCHEMBL23831752 | 0.89 | TRPV1 (0.52) | TRPV1KDRMEN1KMT2AMAPT | |
| SCHEMBL30104912 | 0.88 | TRPV1 (0.51) | TRPV1KDRMEN1KMT2AMAPT | |
| SCHEMBL23831810 | 0.88 | TRPV1 (0.51) | TRPV1KDRMEN1KMT2AMAPT | |
| SCHEMBL23832113 | 0.88 | TRPV1 (0.50) | TRPV1MEN1KMT2AMAPTLMNA | |
| SCHEMBL30105103 | 0.88 | TRPV1 (0.50) | TRPV1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |