SCHEMBL30105973

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)CNC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCC(=O)O)C(C)C)[C@@H](C)O)C(C)C)C(C)C)C(C)C)[C@@H](C)O)C(C)C)[C@@H](C)O)C(C)C)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)O)C(C)C)[C@@H](C)O

nearest known ligand 0.61

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	OPRL1	P41146	5/20	0.61

▸	GLP1R	P43220	4/20	0.58

▸	TFPI	P10646	1/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30495833	0.94	OPRL1 (0.58)	OPRL1GLP1RTFPI
SCHEMBL10694201	0.90	BACE1 (0.60)	GLP1RTFPI
SCHEMBL30906508	0.89	OPRL1 (0.56)	OPRL1GLP1R
SCHEMBL29410012	0.89	BACE1 (0.58)	OPRL1GLP1R
SCHEMBL30176494	0.89	TFPI (0.62)	GLP1RTFPI
SCHEMBL30432618	0.89	GRIN2D (0.49)	GLP1RTFPI
SCHEMBL29379948	0.88	VIPR1 (0.61)	GLP1RTFPI
SCHEMBL30432163	0.88	BACE1 (0.62)	—
SCHEMBL30974088	0.88	BACE1 (0.62)	OPRL1TFPI
SCHEMBL29582767	0.88	BACE1 (0.57)	GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240279316-A1	COMPOSITIONS AND METHODS FOR TREATING ALPHA-SYNUCLEINOPATHIES	ASTRAZENECA AB (SE)	2024-08-22	—	—	US	disclosed