Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189104 | 0.86 | EIF4E (0.44) | MAPTENPP2POLBALDH1A1L3MBTL1 | |
| SCHEMBL27189100 | 0.85 | EIF4E (0.46) | MAPTENPP2POLBLMNAMEN1 | |
| SCHEMBL30106375 | 0.84 | EIF4E (0.45) | MAPTCYP2D6CYP2C9CYP2C19ENPP2 | |
| SCHEMBL27189045 | 0.84 | HRH2 (0.47) | MAPTENPP2POLBLMNAMEN1 | |
| SCHEMBL27189043 | 0.84 | EIF4E (0.42) | ENPP2POLBRAB9AL3MBTL1 | |
| SCHEMBL27189072 | 0.84 | EIF4E (0.45) | POLBLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27189052 | 0.83 | EIF4E (0.43) | ENPP2POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL27189105 | 0.83 | EIF4E (0.44) | MAPTENPP2POLBMEN1KMT2A | |
| SCHEMBL27189050 | 0.82 | TRPV1 (0.50) | MAPTENPP2POLBLMNAMEN1 | |
| SCHEMBL27189042 | 0.82 | EIF4E (0.42) | CYP2D6CYP2C9CYP2C19ENPP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022255764-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | disclosed |