Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189070 | 0.92 | HPGD (0.50) | USP2KDM5BHPGDCD274ALDH1A1 | |
| SCHEMBL29158752 | 0.89 | BCL2L1 (0.52) | USP2KDM5BHPGDCD274ALDH1A1 | |
| SCHEMBL29158654 | 0.89 | USP2 (0.46) | USP2KDM5BHPGDCD274ALDH1A1 | |
| SCHEMBL29158732 | 0.87 | USP2 (0.45) | USP2KDM5BHPGDCD274ALDH1A1 | |
| SCHEMBL29158682 | 0.87 | KDM5B (0.52) | USP2KDM5BHPGDALDH1A1MMP12 | |
| SCHEMBL29158637 | 0.87 | HPGD (0.45) | USP2KDM5BHPGDCD274ALDH1A1 | |
| SCHEMBL29158694 | 0.86 | USP2 (0.47) | USP2KDM5BHPGDCD274ALDH1A1 | |
| SCHEMBL29158913 | 0.86 | EGLN2 (0.49) | USP2KDM5BHPGDCD274ALDH1A1 | |
| SCHEMBL29158719 | 0.86 | CD274 (0.49) | USP2KDM5BHPGDCD274ALDH1A1 | |
| SCHEMBL29159002 | 0.86 | KDM5B (0.52) | USP2KDM5BHPGDCD274RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255764-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | disclosed |