Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30107459 | 0.83 | MAP4K1 (0.53) | MAP4K1 | |
| SCHEMBL30107548 | 0.76 | MAP4K1 (0.60) | MAP4K1 | |
| SCHEMBL11377648 | 0.76 | MAP4K1 (0.60) | MAP4K1 | |
| SCHEMBL30107120 | 0.73 | MAP4K1 (0.53) | MAP4K1 | |
| SCHEMBL11372347 | 0.73 | HSP90AA1 (0.51) | MAP4K1 | |
| SCHEMBL20519527 | 0.73 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL21334401 | 0.73 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL20519529 | 0.73 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL30107424 | 0.72 | MAP4K1 (0.47) | MAP4K1 | |
| SCHEMBL30107161 | 0.72 | MAP4K1 (0.46) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678466-B | Diazanaphthalenes as HPK1 inhibitors | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |