Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 9/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 5/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14719656 | 1.00 | DAO (0.50) | DAODHODHPARP1MMP13PTGS1 | |
| SCHEMBL14719483 | 0.90 | DAO (0.50) | DAODHODHPARP1PTGS1PTGS2 | |
| SCHEMBL16231926 | 0.88 | DAO (0.41) | DAOPARP1 | |
| SCHEMBL14719661 | 0.88 | DAO (0.47) | DAOPARP1 | |
| SCHEMBL16231912 | 0.84 | PARP1 (0.45) | DAOPARP1 | |
| SCHEMBL30159699 | 0.84 | DAO (0.53) | DAOPARP1 | |
| SCHEMBL14718624 | 0.84 | DAO (0.53) | DAOPARP1 | |
| SCHEMBL16231932 | 0.82 | NR3C2 (0.45) | DAOPARP1 | |
| SCHEMBL14719236 | 0.82 | DAO (0.57) | DAOPTGS1PTGS2 | |
| SCHEMBL16228499 | 0.82 | DAO (0.57) | DAODHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666526-A | Oral solid preparation | 武田药品工业株式会社 | 2023-01-31 | — | — | CN | disclosed |
| EP-4114361-A1 | ORAL SOLID PREPARATIONS | Takeda Pharmaceutical Company Limited (JP) | 2023-01-11 | — | — | EP | disclosed |