Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2C | Q8TBX8 | 17/20 | 1.00 |
| ▸ | HTT | P42858 | 16/20 | 1.00 |
| ▸ | PAX8 | Q06710 | 5/20 | 1.00 |
| ▸ | MITF | O75030 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900175 | 1.00 | PIP4K2C (1.00) | PIP4K2CHTTPAX8MITFMEN1 | |
| SCHEMBL899748 | 0.86 | PIP4K2C (1.00) | PIP4K2CHTTPAX8 | |
| SCHEMBL903164 | 0.84 | HTT (1.00) | PIP4K2CHTTPAX8MITFMEN1 | |
| SCHEMBL903184 | 0.82 | HTT (1.00) | PIP4K2CHTTPAX8MITFMEN1 | |
| SCHEMBL900911 | 0.81 | PIP4K2C (1.00) | PIP4K2CHTTPAX8 | |
| SCHEMBL903199 | 0.81 | HTT (1.00) | PIP4K2CHTTPAX8MITFMEN1 | |
| SCHEMBL901247 | 0.80 | PIP4K2C (1.00) | PIP4K2CHTTPAX8 | |
| SCHEMBL900551 | 0.80 | PIP4K2C (1.00) | PIP4K2CHTTPAX8 | |
| SCHEMBL899971 | 0.79 | PIP4K2C (0.71) | PIP4K2CHTTPAX8MITFMEN1 | |
| SCHEMBL900003 | 0.79 | PIP4K2C (1.00) | PIP4K2CHTTPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230096781-A1 | METHODS OF CONTROLLING BODYWEIGHT BY MODULATING PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE BETA ACTIVITY | UNIVERSITY OF CINCINNATI (US) | 2023-03-30 | — | — | US | claimed |
| EP-4114963-A1 | METHODS OF CONTROLLING BODYWEIGHT BY MODULATING PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE BETA ACTIVITY | University of Cincinnati (US) | 2023-01-11 | — | — | EP | claimed |
| CN-118812505-A | PI5P4K gamma inhibitor compound, pharmaceutical composition, and preparation method and application thereof | 贵州医科大学 | 2024-10-22 | — | — | CN | disclosed |
| EP-4364740-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER | Industry-Academic Cooperation Foundation Yonsei University (KR) | 2024-05-08 | — | — | EP | disclosed |
| US-20230096781-A1 | METHODS OF CONTROLLING BODYWEIGHT BY MODULATING PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE BETA ACTIVITY | UNIVERSITY OF CINCINNATI (US) | 2023-03-30 | — | — | US | disclosed |
| EP-4114963-A1 | METHODS OF CONTROLLING BODYWEIGHT BY MODULATING PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE BETA ACTIVITY | University of Cincinnati (US) | 2023-01-11 | — | — | EP | disclosed |
| WO-2023277502-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER | 연세대학교 산학협력단 | 2023-01-05 | — | — | WO | disclosed |