Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30308920 | 1.00 | GRIN1 (0.42) | GRIN1GRIN2ASLC6A4OPRK1GRIN2D | |
| SCHEMBL30308882 | 1.00 | GRIN1 (0.42) | GRIN1GRIN2ASLC6A4OPRK1GRIN2D | |
| SCHEMBL16139853 | 1.00 | GRIN1 (0.42) | GRIN1GRIN2ASLC6A4OPRK1GRIN2D | |
| SCHEMBL16139862 | 1.00 | GRIN1 (0.42) | GRIN1GRIN2ASLC6A4OPRK1GRIN2D | |
| SCHEMBL30308935 | 1.00 | GRIN1 (0.42) | GRIN1GRIN2ASLC6A4OPRK1GRIN2D | |
| SCHEMBL19403831 | 1.00 | GRIN1 (0.42) | GRIN1GRIN2ASLC6A4OPRK1GRIN2D | |
| SCHEMBL30308923 | 1.00 | GRIN1 (0.42) | GRIN1GRIN2ASLC6A4OPRK1GRIN2D | |
| SCHEMBL22005157 | 1.00 | GRIN1 (0.42) | GRIN1GRIN2ASLC6A4OPRK1GRIN2D | |
| SCHEMBL20994020 | 1.00 | GRIN1 (0.42) | GRIN1GRIN2ASLC6A4OPRK1GRIN2D | |
| SCHEMBL21451998 | 0.97 | GRIN1 (0.44) | GRIN1GRIN2ASLC6A4OPRK1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4114821-A1 | ARYLCYCLOHEXYLAMINE DERIVATIVES AND PROCESS FOR PREPARING SAME | Technische Hochschule Köln (DE) | 2023-01-11 | — | — | EP | disclosed |