SCHEMBL30107987

SCHEMBL30107987

CCCC[Sn](CCCC)(CCCC)c1n[nH]c2cc(O[Si](C)(C)C(C)(C)C)ccc12

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.34
CA1 P00915 4/20 0.34
CA9 Q16790 4/20 0.34
GSK3B P49841 1/20 0.31
PREP P48147 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14738482 0.77 ITK (0.40)
SCHEMBL14737848 0.76 MAP2K4 (0.43) GSK3B
SCHEMBL14737185 0.76 GSK3B (0.47) GSK3BTRPA1
SCHEMBL628214 0.75 PDPK1 (0.50) CA12CA1CA9
SCHEMBL14737317 0.74 CA12 (0.33) CA12CA1CA9PREP
SCHEMBL17026535 0.74 CA12 (0.40) CA12CA1CA9PREPTRPA1
SCHEMBL29781791 0.74 CA12 (0.40) CA12CA1CA9PREPTRPA1
SCHEMBL28358722 0.72 KDM4E (0.42)
SCHEMBL14737384 0.70 TTK (0.36)
SCHEMBL14738015 0.68 BACE1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022203399-A1 ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF 주식회사 스탠다임 2022-09-29 WO disclosed