Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.89 |
| ▸ | IGF1R | P08069 | 6/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.72 |
| ▸ | INSR | P06213 | 3/20 | 0.66 |
| ▸ | CDK2 | P24941 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28963870 | 1.00 | EGFR (0.89) | EGFRIGF1RKCNH2INSRCDK2 | |
| SCHEMBL28963871 | 1.00 | EGFR (0.89) | EGFRIGF1RKCNH2INSRCDK2 | |
| SCHEMBL28460789 | 1.00 | EGFR (0.89) | EGFRIGF1RKCNH2INSRCDK2 | |
| SCHEMBL14719279 | 0.94 | EGFR (1.00) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL14719280 | 0.94 | EGFR (1.00) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28468896 | 0.91 | EGFR (0.88) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28942069 | 0.91 | EGFR (0.88) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL29232099 | 0.89 | EGFR (0.89) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28942031 | 0.87 | EGFR (0.72) | EGFRIGF1RKCNH2INSR | |
| SCHEMBL28467332 | 0.87 | EGFR (0.72) | EGFRIGF1RKCNH2INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650974-B | N- [5- (pyrimidine-2-amino) -2, 4-disubstituted phenyl ] -cis-pentadiene amide derivative and application thereof | 天津大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-115650974-A | N- [5- (pyrimidine-2-amino) -2,4-disubstituted phenyl ] -cis-pentadiene amide derivative and application thereof | 天津大学 | 2023-01-31 | — | — | CN | disclosed |