Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 14/20 | 0.59 |
| ▸ | IGF1R | P08069 | 3/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | INSR | P06213 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 4/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.47 |
| ▸ | CDK9 | P50750 | 3/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.47 |
| ▸ | CDK7 | P50613 | 2/20 | 0.47 |
| ▸ | CCNH | P51946 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | CCNK | O75909 | 2/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14663305 | 1.00 | ALK (0.61) | ALKEGFRIGF1RKCNH2INSR | |
| SCHEMBL14718803 | 0.94 | ALK (0.64) | ALKEGFRIGF1RKCNH2INSR | |
| SCHEMBL29974570 | 0.88 | EGFR (0.74) | ALKEGFRIGF1RKCNH2CDK2 | |
| SCHEMBL14663439 | 0.88 | EGFR (0.74) | ALKEGFRIGF1RKCNH2CDK2 | |
| SCHEMBL14663492 | 0.88 | EGFR (0.57) | ALKEGFRIGF1RKCNH2INSR | |
| SCHEMBL30956860 | 0.87 | ALK (0.68) | ALKEGFRIGF1RKCNH2CDK2 | |
| SCHEMBL29232057 | 0.87 | ALK (0.68) | ALKEGFRIGF1RKCNH2CDK2 | |
| SCHEMBL14719276 | 0.86 | EGFR (0.80) | EGFRIGF1RKCNH2INSRCDK2 | |
| SCHEMBL30108177 | 0.85 | FLT3 (0.60) | EGFRIGF1RKCNH2CDK2CDK1 | |
| SCHEMBL14663301 | 0.85 | FLT3 (0.60) | EGFRIGF1RKCNH2CDK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650974-B | N- [5- (pyrimidine-2-amino) -2, 4-disubstituted phenyl ] -cis-pentadiene amide derivative and application thereof | 天津大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-115650974-A | N- [5- (pyrimidine-2-amino) -2,4-disubstituted phenyl ] -cis-pentadiene amide derivative and application thereof | 天津大学 | 2023-01-31 | — | — | CN | disclosed |