Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23283078 | 1.00 | HDAC1 (0.47) | HDAC1HDAC6HDAC8ALDH1A1HPGD | |
| SCHEMBL16211288 | 0.96 | HDAC1 (0.50) | HDAC1HDAC6HDAC8ALDH1A1HPGD | |
| SCHEMBL29879218 | 0.92 | HDAC1 (0.47) | HDAC1HDAC6HDAC8ALDH1A1HPGD | |
| SCHEMBL25980267 | 0.91 | HDAC1 (0.46) | HDAC1HDAC6HDAC8ALDH1A1NPC1 | |
| SCHEMBL23283084 | 0.91 | HDAC1 (0.46) | HDAC1HDAC6HDAC8NPC1RAB9A | |
| SCHEMBL25981788 | 0.88 | HDAC1 (0.47) | HDAC1HDAC6HDAC8ALDH1A1NPC1 | |
| SCHEMBL23283065 | 0.88 | HDAC1 (0.48) | HDAC1HDAC6HDAC8ALDH1A1NPC1 | |
| SCHEMBL29878765 | 0.87 | MEN1 (0.40) | HDAC1HDAC6HDAC8ALDH1A1RAB9A | |
| SCHEMBL25980260 | 0.87 | HDAC1 (0.49) | HDAC1HDAC6HDAC8ALDH1A1NPC1 | |
| SCHEMBL16211519 | 0.86 | HDAC1 (0.49) | HDAC1HDAC6HDAC8ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023073600-A1 | COMPOSITIONS FOR PREVENTING OR TREATING IDIOPATHIC PULMONARY FIBROSIS (IPF) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-05-04 | — | — | WO | disclosed |
| WO-2022203429-A1 | COMPOSITION FOR PREVENTING OR TREATING MULTIPLE SCLEROSIS | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2022-09-29 | — | — | WO | disclosed |