⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28154462 | 0.90 | — | — | |
| Trifluoroacetic Acid SCHEMBL29498756 | 0.84 | CA12 (0.31) | — | |
| Methylpiperazine SCHEMBL28305707 | 0.81 | KDM4E (0.31) | — | |
| SCHEMBL26926379 | 0.78 | — | — | |
| SCHEMBL11173353 | 0.76 | — | — | |
| SCHEMBL12229004 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27259613 | 0.74 | — | — | |
| Sulfamate SCHEMBL28953816 | 0.74 | CA1 (0.30) | — | |
| SCHEMBL4614861 | 0.73 | — | — | |
| SCHEMBL28347663 | 0.69 | CYP2C9 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025070390-A1 | METHOD FOR PRODUCING N-PYRIDYLSULFONAMIDE COMPOUND, PYRIDINE COMPOUND, AND CRYSTAL OF N-PYRIDYLSULFONAMIDE COMPOUND | 第一三共株式会社 | 2025-04-03 | — | — | WO | claimed |
| EP-2900670-A1 | SUBSTITUTED INDAZOL-PYRROLOPYRIMIDINES USEFUL IN THE TREATMENT OF HYPERFOLIFERATIVE DISORDERS | Bayer Pharma Aktiengesellschaft (DE) | 2015-08-05 | — | — | EP | claimed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2025070390-A1 | METHOD FOR PRODUCING N-PYRIDYLSULFONAMIDE COMPOUND, PYRIDINE COMPOUND, AND CRYSTAL OF N-PYRIDYLSULFONAMIDE COMPOUND | 第一三共株式会社 | 2025-04-03 | — | — | WO | disclosed |
| WO-2025070390-A1 | METHOD FOR PRODUCING N-PYRIDYLSULFONAMIDE COMPOUND, PYRIDINE COMPOUND, AND CRYSTAL OF N-PYRIDYLSULFONAMIDE COMPOUND | 第一三共株式会社 | 2025-04-03 | — | — | WO | disclosed |
| US-12065448-B2 | Heteroaryl plasma kallikrein inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-08-20 | — | — | US | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| WO-2023237015-A1 | N-TETRAZOLYL ARYL UREA DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | 杭州壹瑞医药科技有限公司 | 2023-12-14 | — | — | WO | disclosed |
| WO-2023161316-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-31 | — | — | WO | disclosed |
| US-20220298176-A1 | HETEROARYL PLASMA KALLIKREIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-09-22 | — | — | US | disclosed |
| CN-115010712-A | TDO2 inhibitors | 基因泰克公司 | 2022-09-06 | — | — | CN | disclosed |
| EP-2193127-A1 | BENZOTHIAZOLE COMPOUNDS | The Walter and Eliza Hall Institute of Medical Research (AU) | 2010-06-09 | — | — | EP | disclosed |
| CN-101490041-A | 2-heterocycloamino-4-imidazolylpyrimidines as agents for the inhibition of cell proliferation | ASTRAZENECA AB (SE) | 2009-07-22 | — | — | CN | disclosed |
| WO-2009039553-A1 | BENZOTHIAZOLE COMPOUNDS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2009-04-02 | — | — | WO | disclosed |
| CN-100343251-C | Substituted homopiperidinyl benzimidazole compounds, pharmaceutical compositions containing them, process for preparing them and their use as medicaments | JANSSEN PHARMACEUTICA NV (BE) | 2007-10-17 | — | — | CN | disclosed |
| CN-1411460-A | Substituted homopiperidinyl benzimidazole analogues as fundic relaxants | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-16 | — | — | CN | disclosed |
| CN-1026048-C | Use of solsonylurea compounds as herbicide | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-10-05 | — | — | CN | disclosed |
| CN-1018643-B | Process for producing sulfonylurea compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-10-14 | — | — | CN | disclosed |
| CN-1059073-A | Solsonylurea compounds is as the purposes of weed killer herbicide | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1992-03-04 | — | — | CN | disclosed |
| CN-87102123-A | Sulfonylurea compounds, their preparation and their use as herbicides | — | 1987-10-21 | — | — | CN | disclosed |