Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879204 | 1.00 | PTPN11 (0.51) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL24879261 | 0.88 | PTPN11 (0.61) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24878805 | 0.88 | PTPN11 (0.43) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL27216043 | 0.87 | PTPN11 (0.50) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL27453094 | 0.87 | PTPN11 (0.54) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24879156 | 0.83 | PTPN11 (0.53) | PTPN11MAPK3MAPK1 | |
| SCHEMBL27461903 | 0.82 | PTPN11 (0.52) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24879329 | 0.82 | PTPN11 (0.48) | PTPN11MAPK3MAPK1 | |
| SCHEMBL30111094 | 0.81 | PTPN11 (0.47) | PTPN11MAPK3MAPK1 | |
| SCHEMBL24878783 | 0.81 | PTPN11 (0.47) | PTPN11MAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023282702-A1 | SHP2 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-01-12 | — | — | WO | disclosed |