SCHEMBL30111281

SCHEMBL30111281

CCn1cncc1Cn1c(CN2CC[C@@H](Oc3ccnc(COc4ccc(Cl)cc4Cl)c3)C2)nc2ccc(C(=O)O)cc21

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24793373 1.00 GLP1R (0.56) GLP1R
SCHEMBL24791615 1.00 GLP1R (0.56) GLP1R
SCHEMBL30111305 1.00 GLP1R (0.56) GLP1R
SCHEMBL29826429 0.96 GLP1R (0.59) GLP1R
SCHEMBL24791657 0.95 GLP1R (0.54) GLP1R
SCHEMBL30111214 0.95 GLP1R (0.54) GLP1R
SCHEMBL29826112 0.91 GLP1R (0.53) GLP1R
SCHEMBL29826249 0.90 GLP1R (0.64) GLP1R
SCHEMBL29103633 0.90 GLP1R (0.64) GLP1R
SCHEMBL29826111 0.90 GLP1R (0.54) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240262811-A1 BENZIMIDAZOYL GLP-1 RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE CARMOT THERAPEUTICS, INC. 2024-08-08 — — US disclosed
US-20220396569-A1 BENZIMIDAZOYL GLP-1 RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE CARMOT THERAPEUTICS, INC. 2022-12-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220396569-A1 BENZIMIDAZOYL GLP-1 RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE GLP1R, GIPR, GCGR GLP1R 1/4885
US-20240262811-A1 BENZIMIDAZOYL GLP-1 RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE GLP1R, GIPR, GCGR GLP1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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