Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 4/20 | 0.40 |
| ▸ | BCR | P11274 | 4/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21799104 | 1.00 | PTK2 (0.42) | PTK2ABL1BCRIGF1RABCB1 | |
| SCHEMBL20188131 | 0.95 | PTK2 (0.44) | PTK2ABL1BCRABCB1LMNA | |
| SCHEMBL30530287 | 0.95 | PTK2 (0.44) | PTK2ABL1BCRABCB1LMNA | |
| SCHEMBL21799106 | 0.93 | — | — | |
| SCHEMBL20187976 | 0.89 | AURKA (0.45) | AURKA | |
| SCHEMBL30114850 | 0.89 | AURKA (0.45) | AURKA | |
| SCHEMBL20196486 | 0.86 | AURKA (0.47) | ABL1BCRLMNAMAPTAURKA | |
| SCHEMBL30114870 | 0.86 | AURKA (0.47) | ABL1BCRLMNAMAPTAURKA | |
| SCHEMBL21799064 | 0.86 | ABL1 (0.39) | PTK2ABL1BCRABCB1 | |
| SCHEMBL30114857 | 0.86 | ABL1 (0.39) | PTK2ABL1BCRABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139692-B | Heteroaryl amine compounds for modulating hedgehog pathway and methods of making and using the same | 财团法人生物技术开发中心 | 2023-08-25 | — | — | CN | disclosed |
| EP-3544685-B1 | HETROARYLAMINE COMPOUNDS FOR MODULATING THE HEDGEHOG PATHWAY AND PREPARING METHOD AND USES THEREOF | DEV CT BIOTECHNOLOGY (TW) | 2023-01-04 | — | — | EP | disclosed |