Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.39 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188604 | 1.00 | DDR1 (0.39) | DDR1DDR2PIKFYVETRPV1 | |
| SCHEMBL20191139 | 0.89 | HPSE (0.40) | — | |
| SCHEMBL21799100 | 0.85 | ABL1 (0.55) | — | |
| SCHEMBL30114863 | 0.85 | ABL1 (0.55) | — | |
| SCHEMBL20188373 | 0.80 | BCHE (0.45) | — | |
| SCHEMBL30530317 | 0.80 | BCHE (0.45) | — | |
| SCHEMBL20189266 | 0.80 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL20190689 | 0.80 | ABL1 (0.41) | — | |
| SCHEMBL30530284 | 0.76 | ABL1 (0.48) | — | |
| SCHEMBL21799136 | 0.76 | ABL1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139692-B | Heteroaryl amine compounds for modulating hedgehog pathway and methods of making and using the same | 财团法人生物技术开发中心 | 2023-08-25 | — | — | CN | disclosed |
| EP-3544685-B1 | HETROARYLAMINE COMPOUNDS FOR MODULATING THE HEDGEHOG PATHWAY AND PREPARING METHOD AND USES THEREOF | DEV CT BIOTECHNOLOGY (TW) | 2023-01-04 | — | — | EP | disclosed |