Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261190 | 1.00 | BRD4 (0.47) | BRD4LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL261057 | 0.88 | BRD4 (0.47) | BRD4LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL30114968 | 0.88 | BRD4 (0.47) | BRD4LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL31034902 | 0.84 | BRD4 (0.51) | BRD4LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL22904560 | 0.80 | BRD4 (0.48) | BRD4LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL9770038 | 0.80 | BRD4 (0.48) | BRD4LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL25699874 | 0.79 | MEN1 (0.42) | MEN1KMT2APOLBSMN1; SMN2TSHR | |
| SCHEMBL31034917 | 0.78 | BRD4 (0.46) | BRD4LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL7301462 | 0.77 | BRD4 (0.54) | BRD4LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL13378149 | 0.77 | MME (0.44) | LMNAMEN1KMT2APOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443269-A | Substituted pyrimidines and methods of use | 施万生物制药研发IP有限责任公司 | 2022-12-06 | — | — | CN | disclosed |