SCHEMBL30115366

SCHEMBL30115366

C=CS(=O)(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EGFR P00533 16/20 1.00
ERBB2 P04626 6/20 0.67
SRC P12931 2/20 0.67
FYN P06241 1/20 0.67
BLK P51451 1/20 0.67
BMX P51813 1/20 0.67
JAK3 P52333 1/20 0.67
BTK Q06187 1/20 0.67
ERBB4 Q15303 1/20 0.67
LRRK2 Q5S007 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2992732 1.00 EGFR (1.00) EGFRERBB2SRCFYNBLK
SCHEMBL2991092 0.91 EGFR (0.84) EGFRERBB2SRCFYNBLK
SCHEMBL4185005 0.89 EGFR (0.79) EGFRERBB2SRCFYNBLK
SCHEMBL2986366 0.87 EGFR (1.00) EGFRERBB2ERBB4
SCHEMBL27435925 0.83 EGFR (0.72) EGFRERBB2SRCFYNBLK
SCHEMBL7242465 0.81 EGFR (0.68) EGFRERBB2SRCFYNLRRK2
SCHEMBL7128726 0.81 EGFR (0.68) EGFRERBB2SRCFYNBLK
SCHEMBL2680536 0.80 EGFR (1.00) EGFRERBB2SRCFYNBLK
SCHEMBL29359583 0.80 EGFR (1.00) EGFRERBB2SRCFYNBLK
SCHEMBL7238227 0.80 EGFR (0.68) EGFRERBB2SRCFYNLRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230001008-A1 COMPOSITIONS AND METHODS FOR TARGETING CELLULAR MOLECULES KUMQUAT BIOSCIENCES INC. 2023-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230001008-A1 COMPOSITIONS AND METHODS FOR TARGETING CELLULAR MOLECULES CD2BP2, CD47, CD74 EGFR 1892/4885ERBB2 2230/4885SRC 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.