Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.51 |
| ▸ | FGB | P02675 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PLEC | Q15149 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226665 | 1.00 | STING1 (0.82) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226600 | 0.94 | STING1 (0.91) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226717 | 0.92 | STING1 (0.80) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226643 | 0.92 | STING1 (0.76) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226640 | 0.91 | STING1 (0.75) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226634 | 0.90 | STING1 (0.84) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226366 | 0.90 | STING1 (1.00) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28551696 | 0.90 | STING1 (0.80) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226363 | 0.90 | STING1 (0.88) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL29923263 | 0.90 | STING1 (1.00) | STING1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409223-B | Amide compound and medical application thereof as STING inhibitor | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |