SCHEMBL30116701

CC(C)C[C@@H](NC(=O)CNC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](C)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CC(=O)O)NC(=O)[C@@H](N)C(C)C)C(=O)N[C@H](CC(=O)O)C(=O)N[C@H](C)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C(=O)O)[C@H](C)O

nearest known ligand 0.63

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.63

▸	NPY5R	Q15761	8/20	0.55

▸	NPY4R	P50391	7/20	0.55

▸	NPY1R	P25929	6/20	0.55

▸	VIPR1	P32241	4/20	0.55

▸	VIPR2	P41587	3/20	0.55

▸	NR3C1	P04150	1/20	0.54

▸	NPY2R	P49146	5/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30432180	0.92	TFPI (0.62)	TFPINPY5RNPY4RNPY1RVIPR1
SCHEMBL30567730	0.91	TFPI (0.66)	TFPIVIPR1VIPR2NR3C1
SCHEMBL29488765	0.91	TFPI (0.60)	TFPINPY5RNPY4RNPY1RVIPR1
SCHEMBL29648483	0.91	TFPI (0.60)	TFPINPY5RNPY4RNPY1RVIPR1
SCHEMBL30607300	0.89	TFPI (0.67)	TFPIVIPR1NR3C1
SCHEMBL31544066	0.88	NPY4R (0.59)	TFPINPY5RNPY4RNPY1RVIPR1
SCHEMBL30262055	0.88	TFPI (0.62)	TFPIVIPR1VIPR2
SCHEMBL31683486	0.88	TFPI (0.58)	TFPINPY5RNPY4RNPY1RVIPR1
SCHEMBL30648448	0.87	TFPI (0.70)	TFPIVIPR1VIPR2NR3C1
SCHEMBL29679580	0.87	TFPI (0.58)	TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4096697-A1	PEPTIDES USEFUL IN PRESERVATION AND/OR RESTORATION OF FUNCTIONAL PANCREATIC ISLETS AND IN TREATING DIABETES	The National Institute for Biotechnology in the Negev Ltd. (IL)	2022-12-07	—	—	EP	disclosed