SCHEMBL30116708

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](CC(C)C)C(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@H](CCCCN)C(=O)N[C@@H](C(=O)N[C@H](Cc1ccccc1)C(=O)O)[C@H](C)O)[C@@H](C)CC

nearest known ligand 0.60

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	VIPR2	P41587	6/20	0.60

▸	VIPR1	P32241	4/20	0.60

▸	TFPI	P10646	1/20	0.59

▸	IL23R	Q5VWK5	5/20	0.58

▸	KEAP1	Q14145	1/20	0.57

▸	GLP1R	P43220	1/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30974522	0.94	VIPR1 (0.61)	VIPR2VIPR1TFPI
SCHEMBL30782799	0.90	VIPR2 (0.54)	VIPR2VIPR1IL23R
SCHEMBL30262251	0.90	TFPI (0.63)	VIPR2VIPR1TFPIIL23RGLP1R
SCHEMBL14588774	0.89	TFPI (0.60)	TFPIIL23RKEAP1
SCHEMBL30168689	0.89	TFPI (0.57)	VIPR2VIPR1TFPIIL23R
SCHEMBL29694509	0.89	VIPR2 (0.66)	VIPR2VIPR1TFPI
SCHEMBL30495717	0.88	TFPI (0.66)	VIPR2VIPR1TFPIGLP1R
SCHEMBL29770069	0.88	TFPI (0.63)	TFPIIL23RKEAP1
SCHEMBL29694508	0.88	VIPR2 (0.66)	VIPR2VIPR1TFPIGLP1R
SCHEMBL30385132	0.87	TFPI (0.63)	TFPIIL23RKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4096697-A1	PEPTIDES USEFUL IN PRESERVATION AND/OR RESTORATION OF FUNCTIONAL PANCREATIC ISLETS AND IN TREATING DIABETES	The National Institute for Biotechnology in the Negev Ltd. (IL)	2022-12-07	—	—	EP	disclosed