SCHEMBL30116865

SCHEMBL30116865

CC(C)C[C@@H](C(=O)O)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
FABP5 Q01469 3/20 0.38
FABP7 O15540 2/20 0.38
CASP3 P42574 3/20 0.36
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
CTSL P07711 1/20 0.35
CTSB P07858 1/20 0.35
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35
EPHX2 P34913 1/20 0.34
MDM4 O15151 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26312165 1.00 KMT2A (0.38) KMT2AFABP5FABP7CASP3MMP2
SCHEMBL26314523 1.00 KMT2A (0.38) KMT2AFABP5FABP7CASP3MMP2
SCHEMBL29400870 0.90 FABP5 (0.43) KMT2AFABP5FABP7CASP3CTSL
SCHEMBL3728170 0.90 FABP5 (0.43) KMT2AFABP5FABP7CASP3CTSL
SCHEMBL29908641 0.90 FABP5 (0.43) KMT2AFABP5FABP7CASP3CTSL
SCHEMBL31732619 0.90 FABP5 (0.43) KMT2AFABP5FABP7CASP3CTSL
SCHEMBL119027 0.90 FABP5 (0.43) KMT2AFABP5FABP7CASP3CTSL
SCHEMBL29401170 0.90 FABP5 (0.43) KMT2AFABP5FABP7CASP3CTSL
SCHEMBL30896130 0.90 FABP5 (0.43) KMT2AFABP5FABP7CASP3CTSL
SCHEMBL1486163 0.90 FABP5 (0.43) KMT2AFABP5FABP7CASP3CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295221-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-09-21 US disclosed
EP-4144747-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-03-08 EP disclosed
CN-115698032-A Efficient peptide condensation of difficult sequences 中外制药株式会社 2023-02-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295221-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES NGLY1, VIP, DNPEP KMT2A 3727/4885FABP5 2084/4885FABP7 1329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.