Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24065757 | 1.00 | NTRK1 (0.64) | NTRK1 | |
| SCHEMBL30118856 | 0.93 | NTRK1 (0.60) | NTRK1 | |
| SCHEMBL24065704 | 0.93 | NTRK1 (0.60) | NTRK1 | |
| SCHEMBL30118885 | 0.92 | NTRK1 (0.60) | NTRK1 | |
| SCHEMBL30250731 | 0.92 | NTRK1 (0.60) | NTRK1 | |
| SCHEMBL24065739 | 0.92 | NTRK1 (0.60) | NTRK1 | |
| SCHEMBL24077420 | 0.86 | NTRK1 (0.57) | NTRK1 | |
| SCHEMBL17111578 | 0.78 | NTRK1 (1.00) | NTRK1 | |
| SCHEMBL25747902 | 0.78 | NTRK1 (0.49) | NTRK1 | |
| SCHEMBL17111464 | 0.77 | NTRK1 (0.61) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667241-B | Trka inhibitors | 伊莱利利公司 | 2024-04-16 | — | — | CN | disclosed |
| EP-4126842-A1 | TRKA INHIBITOR | ELI LILLY AND COMPANY (US) | 2023-02-08 | — | — | EP | disclosed |
| CN-115667241-A | TrkA inhibitors | 伊莱利利公司 | 2023-01-31 | — | — | CN | disclosed |