Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.69 |
| ▸ | DDB1 | Q16531 | 14/20 | 0.69 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25023330 | 0.86 | CRBN (0.70) | CRBNDDB1NAMPT | |
| SCHEMBL24816843 | 0.85 | CRBN (0.69) | CRBNDDB1 | |
| SCHEMBL25768264 | 0.82 | CRBN (0.65) | CRBNDDB1 | |
| SCHEMBL30258522 | 0.82 | CRBN (1.00) | CRBNDDB1 | |
| SCHEMBL26826457 | 0.82 | CRBN (1.00) | CRBNDDB1 | |
| SCHEMBL27363539 | 0.81 | CRBN (0.63) | CRBNDDB1 | |
| SCHEMBL23538529 | 0.81 | CRBN (0.62) | CRBNDDB1 | |
| SCHEMBL24753068 | 0.81 | CRBN (0.62) | CRBNDDB1 | |
| SCHEMBL24752738 | 0.79 | CRBN (0.60) | CRBNDDB1 | |
| SCHEMBL23551579 | 0.79 | CRBN (0.77) | CRBNDDB1NAMPTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096858-A1 | COMPOUNDS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| EP-4351583-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261250-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |