Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29160928 | 0.99 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19 | |
| SCHEMBL26924730 | 0.91 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19 | |
| SCHEMBL30020092 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19 | |
| SCHEMBL2434340 | 0.86 | MEN1 (0.58) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19 | |
| SCHEMBL25305267 | 0.85 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19 | |
| Hydrochloric Acid SCHEMBL16616208 | 0.85 | MEN1 (0.57) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19 | |
| SCHEMBL27142689 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19 | |
| SCHEMBL27153503 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19 | |
| SCHEMBL22878316 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19 | |
| SCHEMBL29927976 | 0.83 | GRIN2B (0.54) | SMN1; SMN2NPC1RAB9AGRIN2BCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323352-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022253309-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND APPLICATION THEREOF | 首药控股(北京)股份有限公司 | 2022-12-08 | — | — | WO | disclosed |