Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.53 |
| ▸ | STAT6 | P42226 | 10/20 | 0.47 |
| ▸ | SYK | P43405 | 3/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20759881 | 1.00 | JAK3 (0.53) | JAK3STAT6SYKPTK2PTK2B | |
| SCHEMBL30122076 | 0.91 | STAT6 (0.58) | JAK3STAT6SYK | |
| SCHEMBL20760050 | 0.91 | STAT6 (0.58) | JAK3STAT6SYK | |
| SCHEMBL20759882 | 0.88 | JAK3 (0.53) | JAK3STAT6SYK | |
| SCHEMBL30121692 | 0.88 | JAK3 (0.53) | JAK3STAT6SYK | |
| SCHEMBL20759863 | 0.87 | JAK2 (0.52) | JAK3STAT6SYK | |
| SCHEMBL30121840 | 0.87 | JAK2 (0.52) | JAK3STAT6SYK | |
| SCHEMBL20760183 | 0.87 | SYK (0.49) | JAK3STAT6SYK | |
| SCHEMBL30121873 | 0.87 | SYK (0.49) | JAK3STAT6SYK | |
| SCHEMBL20761180 | 0.86 | SYK (0.51) | JAK3STAT6SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032630-B | Compound, pharmaceutical composition, application and application thereof | 北京韩美药品有限公司 | 2022-12-16 | — | — | CN | disclosed |