SCHEMBL30121912

SCHEMBL30121912

O=C1CCC(NC(=O)c2c[nH]c3nccc(Cl)c23)C(=O)N1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 20/20 0.56
▸ BRD4 O60885 2/20 0.53
▸ DDB1 Q16531 4/20 0.49
▸ IKZF3 Q9UKT9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23413598 1.00 CRBN (0.56) CRBNBRD4DDB1IKZF3
SCHEMBL23412691 0.83 CRBN (0.54) CRBNBRD4DDB1IKZF3
SCHEMBL23453384 0.76 CRBN (0.61) CRBNBRD4DDB1IKZF3
SCHEMBL23413576 0.76 CRBN (0.53) CRBNBRD4DDB1IKZF3
SCHEMBL20811955 0.75 CRBN (0.72) CRBNBRD4DDB1IKZF3
SCHEMBL23812272 0.74 CRBN (0.68) CRBNBRD4DDB1IKZF3
SCHEMBL23799194 0.74 CRBN (0.72) CRBNBRD4DDB1IKZF3
SCHEMBL23453743 0.73 CRBN (0.55) CRBNBRD4DDB1IKZF3
SCHEMBL20128669 0.73 CRBN (0.71) CRBNBRD4DDB1IKZF3
SCHEMBL30918268 0.73 CRBN (0.71) CRBNBRD4DDB1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025136129-A1 TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET PROTEIN KINASE C CAPTOR THERAPEUTICS S.A. (PL) 2025-06-26 — — WO disclosed
EP-4347579-A1 TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN Captor Therapeutics S.A. (PL) 2024-04-10 — — EP disclosed
WO-2022253713-A1 TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN CAPTOR THERAPEUTICS S.A. (PL) 2022-12-08 — — WO disclosed
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