Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BUB1 | O43683 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075362 | 1.00 | TP53 (0.48) | TP53ALDH1A1KDM4EPOLBP2RY14 | |
| SCHEMBL16796451 | 0.91 | TP53 (0.44) | TP53ALDH1A1KDM4EPOLBP2RY14 | |
| SCHEMBL15964665 | 0.89 | CYP1A2 (0.54) | TP53ALDH1A1KDM4EPOLBP2RY14 | |
| SCHEMBL29831851 | 0.89 | CYP1A2 (0.54) | TP53ALDH1A1KDM4EPOLBP2RY14 | |
| SCHEMBL2921176 | 0.88 | SMN1; SMN2 (0.52) | TP53ALDH1A1KDM4EPOLBP2RY14 | |
| SCHEMBL17611623 | 0.87 | TP53 (0.50) | TP53ALDH1A1KDM4EPOLBP2RY14 | |
| SCHEMBL175092 | 0.87 | TP53 (0.47) | TP53ALDH1A1KDM4EPOLBP2RY14 | |
| SCHEMBL30223258 | 0.87 | TP53 (0.47) | TP53ALDH1A1KDM4EPOLBP2RY14 | |
| SCHEMBL23070362 | 0.87 | PTGER1 (0.43) | TP53ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL16796429 | 0.87 | PTGER1 (0.48) | TP53ALDH1A1KDM4ECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867557-B | Azepine condensed ring compound and medical application thereof | 中国医药研究开发中心有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115867557-A | Azepine fused ring compounds and medical application thereof | 中国医药研究开发中心有限公司 | 2023-03-28 | — | — | CN | disclosed |
| WO-2022258052-A1 | HETEROCYCLIC LACTAM COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-12-15 | — | — | WO | disclosed |