Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 18/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11890643 | 0.89 | TLR8 (0.44) | IRAK4TLR8ALDH1A1MAPTHTT | |
| SCHEMBL31559923 | 0.88 | IRAK4 (0.41) | IRAK4MAPTHTT | |
| SCHEMBL29042022 | 0.87 | IRAK4 (0.39) | IRAK4TLR8ALDH1A1MAPTHTT | |
| SCHEMBL29042026 | 0.87 | IRAK4 (0.39) | IRAK4TLR8ALDH1A1MAPTHTT | |
| SCHEMBL21810482 | 0.85 | TLR8 (0.36) | IRAK4TLR8ALDH1A1MAPTHTT | |
| SCHEMBL30676504 | 0.83 | IRAK4 (0.36) | IRAK4TLR8ALDH1A1MAPTHTT | |
| SCHEMBL29041967 | 0.82 | IRAK4 (0.43) | IRAK4TLR8ALDH1A1MAPTHTT | |
| SCHEMBL15910733 | 0.82 | IRAK4 (0.45) | IRAK4TLR8ALDH1A1MAPT | |
| SCHEMBL27004828 | 0.82 | IRAK4 (0.44) | IRAK4TLR8 | |
| SCHEMBL25339190 | 0.82 | TLR8 (0.40) | IRAK4TLR8ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023198114-A1 | ALK2 KINASE INHIBITOR | 杭州邦顺制药有限公司 | 2023-10-19 | — | — | WO | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-115572260-A | Aryl ether compound and use thereof | 四川科伦博泰生物医药股份有限公司 | 2023-01-06 | — | — | CN | disclosed |