Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PDE1A | P54750 | 5/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.37 |
| ▸ | TNKS | O95271 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28956488 | 1.00 | IRAK4 (0.42) | IRAK4MAPK1PDE4DPDE1APDE1B | |
| SCHEMBL17678304 | 0.93 | IRAK4 (0.46) | IRAK4MAPK1TNKS | |
| SCHEMBL17678315 | 0.90 | IRAK4 (0.44) | IRAK4MAPK1TNKS | |
| SCHEMBL10060453 | 0.88 | IRAK4 (0.42) | IRAK4MAPK1TNKS | |
| SCHEMBL15328409 | 0.88 | IRAK4 (0.44) | IRAK4MAPK1PDE1BPDE1CTNKS | |
| SCHEMBL30613534 | 0.85 | LRRK2 (0.39) | IRAK4TNKS | |
| SCHEMBL29041937 | 0.85 | LRRK2 (0.39) | IRAK4TNKS | |
| SCHEMBL21026361 | 0.83 | IRAK4 (0.54) | IRAK4PIK3CDTNKS | |
| SCHEMBL30613532 | 0.81 | IRAK4 (0.37) | IRAK4MAPK1TNKS | |
| SCHEMBL29041994 | 0.81 | IRAK4 (0.37) | IRAK4MAPK1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023198114-A1 | ALK2 KINASE INHIBITOR | 杭州邦顺制药有限公司 | 2023-10-19 | — | — | WO | disclosed |
| CN-115572260-A | Aryl ether compound and use thereof | 四川科伦博泰生物医药股份有限公司 | 2023-01-06 | — | — | CN | disclosed |