SCHEMBL30123123

SCHEMBL30123123

CC(C)C[C@H](N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ERAP2 Q6P179 8/20 0.76
▸ ECE1 P42892 7/20 0.66
▸ ACE P12821 2/20 0.62
▸ IL1RN P18510 6/20 0.61
▸ ERAP1 Q9NZ08 5/20 0.61
▸ ANPEP P15144 1/20 0.58
▸ MMP1 P03956 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31042843 0.94 ERAP2 (0.73) ERAP2ECE1ACEIL1RNERAP1
SCHEMBL29816206 0.94 ERAP2 (0.67) ERAP2ECE1ACEIL1RNERAP1
SCHEMBL30004587 0.93 ERAP2 (0.67) ERAP2ECE1ACEIL1RNERAP1
SCHEMBL31074338 0.93 ERAP2 (0.67) ERAP2ECE1ACEIL1RNERAP1
SCHEMBL30839328 0.93 ERAP2 (0.73) ERAP2ECE1ACEIL1RNERAP1
SCHEMBL30051190 0.92 ECE1 (0.74) ERAP2ECE1ACEIL1RNERAP1
SCHEMBL14940856 0.92 ECE1 (0.77) ERAP2ECE1ACEERAP1ANPEP
SCHEMBL29531224 0.92 ECE1 (0.77) ERAP2ECE1ACEERAP1ANPEP
SCHEMBL11589639 0.92 ECE1 (0.77) ERAP2ECE1ACEERAP1ANPEP
SCHEMBL29448679 0.92 ECE1 (0.77) ERAP2ECE1ACEERAP1ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110437336-B Proteins specific for BAFF and B7RP1 and uses thereof 美国安进公司 2024-08-27 — — CN disclosed
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 — — EP disclosed
US-20230212297-A1 BISPECIFIC FC MOLECULES AMGEN INC. 2023-07-06 — — US disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 — — WO disclosed
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