Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 14/20 | 0.60 |
| ▸ | PDE4A | P27815 | 9/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 8/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519473 | 1.00 | PDE10A (0.60) | PDE10APDE4APDE4BNPC1RAB9A | |
| SCHEMBL4724444 | 0.88 | PDE10A (0.76) | PDE10APDE4APDE4BNPC1RAB9A | |
| SCHEMBL30123130 | 0.88 | PDE10A (0.76) | PDE10APDE4APDE4BNPC1RAB9A | |
| SCHEMBL4167200 | 0.84 | PDE10A (0.61) | PDE10APDE4APDE4BNPC1RAB9A | |
| SCHEMBL3270119 | 0.82 | PDE10A (0.60) | PDE10APDE4APDE4BLGALS3PDE4D | |
| SCHEMBL3269597 | 0.82 | PDE10A (0.77) | PDE10APDE4APDE4BLGALS3PDE4D | |
| SCHEMBL30122876 | 0.82 | PDE10A (0.77) | PDE10APDE4APDE4BLGALS3PDE4D | |
| SCHEMBL5519916 | 0.81 | PDE10A (0.64) | PDE10APDE4APDE4BLGALS3PDE4D | |
| SCHEMBL4154400 | 0.80 | PDE10A (0.68) | PDE10APDE4APDE4BNPC1RAB9A | |
| SCHEMBL4153844 | 0.79 | PDE10A (0.59) | PDE10APDE4APDE4BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103161-A1 | COMPOSITIONS AND USES THEREOF | BenevolentAI Cambridge Limited (GB) | 2022-12-21 | — | — | EP | disclosed |
| CN-115484938-A | Composition and use thereof | 博善人工智能剑桥有限公司 | 2022-12-16 | — | — | CN | disclosed |