SCHEMBL30123399

SCHEMBL30123399

NC(=O)CC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MME P08473 4/20 0.51
BACE1 P56817 6/20 0.51
NAALAD2 Q9Y3Q0 1/20 0.49
GNPAT O15228 1/20 0.47
ACE P12821 2/20 0.47
CPA1 P15085 2/20 0.47
ACE2 Q9BYF1 2/20 0.47
CTSD P07339 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381316 0.94 MME (0.55) MMEBACE1NAALAD2GNPATACE
SCHEMBL8821945 0.94 MME (0.55) MMEBACE1NAALAD2GNPATACE
SCHEMBL2980533 0.94 MME (0.57) MMEBACE1NAALAD2ACECPA1
SCHEMBL5970186 0.94 MME (0.57) MMEBACE1NAALAD2ACECPA1
SCHEMBL30903452 0.93 BACE1 (0.57) MMEBACE1NAALAD2CTSD
SCHEMBL29603611 0.91 NAALAD2 (0.60) MMEBACE1NAALAD2CTSD
SCHEMBL29531169 0.91 NAALAD2 (0.60) MMEBACE1NAALAD2CTSD
SCHEMBL29603574 0.91 NAALAD2 (0.60) MMEBACE1NAALAD2CTSD
SCHEMBL31474554 0.91 BACE1 (0.56) MMEBACE1NAALAD2GNPATCTSD
SCHEMBL29725302 0.91 BACE1 (0.54) MMEBACE1GNPATCTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 EP disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 WO disclosed