Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 15/20 | 0.65 |
| ▸ | PDE4A | P27815 | 7/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.47 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272337 | 1.00 | PDE10A (0.65) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL3269511 | 0.90 | PDE10A (0.80) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL30123215 | 0.90 | PDE10A (0.80) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL30123240 | 0.89 | PDE10A (0.81) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL3274824 | 0.89 | PDE10A (0.81) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL3269569 | 0.85 | PDE10A (0.56) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL3270782 | 0.79 | PDE10A (1.00) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL29368113 | 0.79 | PDE10A (1.00) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL4161920 | 0.78 | PDE10A (0.80) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL4146861 | 0.78 | PDE10A (0.80) | PDE10APDE4APDE4BPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103161-A1 | COMPOSITIONS AND USES THEREOF | BenevolentAI Cambridge Limited (GB) | 2022-12-21 | — | — | EP | disclosed |
| CN-115484938-A | Composition and use thereof | 博善人工智能剑桥有限公司 | 2022-12-16 | — | — | CN | disclosed |