Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.38 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.38 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.38 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24719664 | 1.00 | MAPKAPK2 (0.45) | MAPKAPK2PRKDCCCNCCDK8FYN | |
| Bromide SCHEMBL29182796 | 0.99 | MAPKAPK2 (0.44) | MAPKAPK2PRKDCCCNCCDK8FYN | |
| SCHEMBL30124375 | 0.90 | MAPKAPK2 (0.43) | MAPKAPK2FYNMAPTSRCCHEK1 | |
| SCHEMBL24951667 | 0.90 | MAPKAPK2 (0.43) | MAPKAPK2MAPTSRCCHEK1AURKA | |
| SCHEMBL24719366 | 0.90 | MAPKAPK2 (0.43) | MAPKAPK2FYNMAPTSRCCHEK1 | |
| SCHEMBL24720315 | 0.90 | AURKA (0.45) | MAPKAPK2CDK8FYNMAPTSRC | |
| SCHEMBL30931091 | 0.89 | PRKD1 (0.41) | PRKDCMAPTLMNATP53AURKA | |
| SCHEMBL24719338 | 0.89 | PRKD1 (0.41) | PRKDCMAPTLMNATP53AURKA | |
| SCHEMBL24719739 | 0.88 | MAPT (0.47) | PRKDCFYNMAPTLMNATP53 | |
| SCHEMBL24952054 | 0.88 | MAPKAPK2 (0.43) | MAPKAPK2CCNCCDK8SRCCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351560-A1 | ANTICANCER COMPOUNDS | The Regents of the University of California (US) | 2024-04-17 | — | — | EP | disclosed |
| CN-117794525-A | Anticancer compounds | 加利福尼亚大学董事会 | 2024-03-29 | — | — | CN | disclosed |
| WO-2022261204-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-15 | — | — | WO | disclosed |