Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30127389 | 1.00 | PIK3CD (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30125750 | 1.00 | PIK3CD (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30126517 | 1.00 | PIK3CD (0.51) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30127558 | 0.96 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30125786 | 0.96 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30125952 | 0.96 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30126934 | 0.96 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30126904 | 0.88 | PIK3CD (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30127470 | 0.87 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPIK3CGPDE4B | |
| SCHEMBL30125765 | 0.86 | EGFR (0.51) | EPHB4ERBB2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266458-A1 | 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |