Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30126635 | 1.00 | EGFR (0.55) | EGFRSRCDRD2KDRERBB2 | |
| SCHEMBL30127211 | 1.00 | EGFR (0.55) | EGFRSRCDRD2KDRERBB2 | |
| SCHEMBL30126843 | 1.00 | EGFR (0.55) | EGFRSRCDRD2KDRERBB2 | |
| SCHEMBL30127437 | 0.96 | EGFR (0.54) | EGFRSRCDRD2KDRERBB2 | |
| SCHEMBL30127576 | 0.96 | EGFR (0.54) | EGFRSRCDRD2KDRERBB2 | |
| SCHEMBL30127367 | 0.96 | EGFR (0.54) | EGFRSRCDRD2KDRERBB2 | |
| SCHEMBL30126646 | 0.96 | EGFR (0.54) | EGFRSRCDRD2KDRERBB2 | |
| SCHEMBL30126811 | 0.91 | EGFR (0.54) | EGFRERBB2 | |
| SCHEMBL30125737 | 0.91 | EGFR (0.54) | EGFRERBB2 | |
| SCHEMBL30126156 | 0.91 | EGFR (0.54) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266458-A1 | 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |