SCHEMBL30129043

SCHEMBL30129043

CC(C)(C)Nc1nc(Cc2ccccc2)nc2nc[nH]c12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.68
PDE4B Q07343 1/20 0.68
PDE4C Q08493 1/20 0.68
PDE4D Q08499 1/20 0.68
SYK P43405 1/20 0.52
CDK1 P06493 3/20 0.48
NUDT1 P36639 2/20 0.46
LMNA P02545 3/20 0.45
TSHR P16473 3/20 0.45
CYP1A2 P05177 3/20 0.45
CYP2D6 P10635 3/20 0.45
MAPK1 P28482 2/20 0.45
CDK2 P24941 2/20 0.45
ADORA3 P0DMS8 2/20 0.45
ADORA2A P29274 1/20 0.45
TOP2A P11388 2/20 0.43
HTT P42858 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
IP6K1 Q92551 1/20 0.43
HSD17B10 Q99714 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1365498 1.00 PDE4A (0.68) PDE4APDE4BPDE4CPDE4DSYK
SCHEMBL16147211 0.86 PDE4A (0.75) PDE4APDE4BPDE4CPDE4DCDK1
SCHEMBL16147214 0.83 PDE4A (0.78) PDE4APDE4BPDE4CPDE4DSYK
SCHEMBL16145949 0.81 PDE4A (0.74) PDE4APDE4BPDE4CPDE4DCDK1
SCHEMBL16146389 0.80 PDE4A (0.65) PDE4APDE4BPDE4CPDE4DCDK1
SCHEMBL4638059 0.79 PDE4A (0.71) PDE4APDE4BPDE4CPDE4DCDK1
SCHEMBL30523448 0.77 PDE4A (0.68) PDE4APDE4BPDE4CPDE4DCDK1
SCHEMBL104931 0.76 PDE4A (0.64) PDE4APDE4BPDE4CPDE4DCDK1
SCHEMBL16146158 0.76 PDE4A (0.64) PDE4APDE4BPDE4CPDE4DCDK1
SCHEMBL29557469 0.76 PDE4A (0.64) PDE4APDE4BPDE4CPDE4DCDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4409031-A1 METHODS FOR BIAS-FREE QUANTIFICATION OF RNA Chronix Biomedical (US) 2024-08-07 EP disclosed
WO-2023055824-A1 METHODS FOR BIAS-FREE QUANTIFICATION OF RNA CHRONIX BIOMEDICAL (US) 2023-04-06 WO disclosed
EP-4127214-A2 METHODS FOR PRECISE AND BIAS-FREE QUANTIFICATION OF CELL-FREE DNA Chronix Biomedical (US) 2023-02-08 EP disclosed