Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.48 |
| ▸ | CDK1 | P06493 | 4/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21884109 | 0.80 | CCNE2 (0.48) | HTTLMNAMAPTMAPK1GFER | |
| SCHEMBL30476574 | 0.79 | CCNE2 (0.48) | LMNAMAPTMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL2317472 | 0.79 | CCNE2 (0.48) | LMNAMAPTMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL30013436 | 0.79 | CCNE2 (0.48) | LMNAMAPTMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL2359481 | 0.79 | CCNE2 (0.48) | LMNAMAPTMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL2317462 | 0.79 | CCNE2 (0.48) | LMNAMAPTMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL20895831 | 0.79 | CCNE2 (0.48) | LMNAMAPTMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL20895830 | 0.79 | CCNE2 (0.48) | LMNAMAPTMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL30130604 | 0.79 | CCNE2 (0.48) | LMNAMAPTMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL19278523 | 0.77 | CDK2 (0.48) | HTTLMNAMAPTMAPK1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115176005-A | Compositions and methods for treating hemoglobinopathies | 诺华股份有限公司 | 2022-10-11 | — | — | CN | disclosed |