Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | HTT | P42858 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | XBP1 | P17861 | 1/20 | 0.64 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096025 | 1.00 | MAPT (0.75) | MAPTMEN1KMT2AHTTRAB9A | |
| Chlorobenzene SCHEMBL27823042 | 0.91 | MAPT (0.68) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL5597699 | 0.87 | KMT2A (0.90) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL30101230 | 0.87 | KMT2A (0.90) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL30069239 | 0.86 | MAPT (1.00) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL17609423 | 0.86 | MAPT (1.00) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL2295426 | 0.86 | MAPT (0.71) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL2093508 | 0.86 | MAPT (0.57) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL17925886 | 0.86 | MEN1 (0.57) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL2096021 | 0.85 | MAPT (0.70) | MAPTMEN1KMT2AHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208256-A1 | TARGETED PROTEIN DEGRADATION COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海汇伦医药股份有限公司 | 2024-10-10 | — | — | WO | disclosed |
| WO-2022250069-A1 | SULFUR-CONTAINING PYRAZOLE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT INCLUDING SULFUR-CONTAINING PYRAZOLE COMPOUND AS ACTIVE INGREDIENT | 三井化学アグロ株式会社 | 2022-12-01 | — | — | WO | disclosed |