Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723609 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRHTTLMNATP53 | |
| SCHEMBL23723520 | 0.92 | TSHR (0.42) | SMN1; SMN2TSHRHTTLMNATP53 | |
| SCHEMBL30132094 | 0.92 | TSHR (0.42) | SMN1; SMN2TSHRHTTLMNATP53 | |
| SCHEMBL30132105 | 0.90 | GRM1 (0.42) | SMN1; SMN2TSHRHTTLMNATP53 | |
| SCHEMBL23723564 | 0.90 | GRM1 (0.42) | SMN1; SMN2TSHRHTTLMNATP53 | |
| SCHEMBL23723808 | 0.90 | GRM1 (0.38) | SMN1; SMN2TSHRLMNATP53ALDH1A1 | |
| SCHEMBL30132062 | 0.90 | GRM1 (0.38) | SMN1; SMN2TSHRLMNATP53ALDH1A1 | |
| SCHEMBL23723692 | 0.86 | MAPT (0.40) | SMN1; SMN2LMNATP53ALDH1A1MAPT | |
| SCHEMBL30132087 | 0.86 | MAPT (0.40) | SMN1; SMN2LMNATP53ALDH1A1MAPT | |
| SCHEMBL23723650 | 0.85 | PDE9A (0.38) | SMN1; SMN2TSHRALDH1A1POLBPDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |