Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.69 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.57 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.56 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.56 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24991548 | 1.00 | CRBN (0.69) | CRBNIKZF2GSPT1DDB1CYP2C19 | |
| Hydrochloric Acid SCHEMBL25280592 | 0.99 | CRBN (0.67) | CRBNIKZF2GSPT1DDB1CYP2C19 | |
| SCHEMBL29188614 | 0.91 | CRBN (0.66) | CRBNIKZF2GSPT1DDB1CYP2C19 | |
| SCHEMBL25227548 | 0.91 | CRBN (0.69) | CRBNGSPT1 | |
| SCHEMBL25228921 | 0.89 | CRBN (0.70) | CRBNIKZF2GSPT1DDB1CYP2C19 | |
| SCHEMBL24600532 | 0.88 | CRBN (0.69) | CRBNIKZF2GSPT1DDB1CYP2C19 | |
| SCHEMBL68272 | 0.88 | CRBN (0.72) | CRBNIKZF2GSPT1DDB1CYP2C19 | |
| SCHEMBL31117059 | 0.88 | CRBN (0.72) | CRBNIKZF2GSPT1DDB1CYP2C19 | |
| SCHEMBL25234569 | 0.88 | CRBN (0.69) | CRBNIKZF2GSPT1DDB1CYP2C19 | |
| SCHEMBL25469611 | 0.88 | CRBN (0.69) | CRBNIKZF2GSPT1DDB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688771-A1 | NOVEL FAK DEGRADER COMPOUNDS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025096706-A1 | MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |
| WO-2025096771-A1 | MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |
| EP-4461730-A1 | PROTEIN DEGRADERS DEVELOPED ON BASIS OF BCL-2 FAMILY PROTEIN LIGAND COMPOUNDS AND USE THEREOF | Shanghaitech University (CN) | 2024-11-13 | — | — | EP | disclosed |
| EP-4380582-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE DEGRADATION OF ENGINEERED PROTEINS | Celgene Corporation (US) | 2024-06-12 | — | — | EP | disclosed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |
| WO-2023015283-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE DEGRADATION OF ENGINEERED PROTEINS | CELGENE CORPORATION (US) | 2023-02-09 | — | — | WO | disclosed |