SCHEMBL30132408

SCHEMBL30132408

CC(C)(O)Cn1ncc2cc(-c3ccc(C(=O)N4[C@@H]5CC[C@H]4[C@@H](N)C5)cc3-c3ccc(C#N)c(F)c3)c(F)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20512750 1.00 KDM1A (1.00) KDM1A
SCHEMBL20512466 0.93 KDM1A (1.00) KDM1A
SCHEMBL20512933 0.93 KDM1A (1.00) KDM1A
SCHEMBL20512934 0.93 KDM1A (1.00) KDM1A
SCHEMBL20512505 0.91 KDM1A (1.00) KDM1A
SCHEMBL21824288 0.88 KDM1A (0.84) KDM1A
SCHEMBL21824289 0.88 KDM1A (0.84) KDM1A
SCHEMBL20512818 0.88 KDM1A (1.00) KDM1A
SCHEMBL29926606 0.88 KDM1A (1.00) KDM1A
SCHEMBL29927132 0.88 KDM1A (0.78) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3381896-B1 BIPHENYL COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO LTD (JP) 2023-01-18 EP claimed