Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417375 | 0.99 | MAPT (0.45) | MAPTBCHECYP2C19GUSBMAOB | |
| SCHEMBL30132716 | 0.99 | MAPT (0.45) | MAPTBCHECYP2C19GUSBMAOB | |
| SCHEMBL30132715 | 0.99 | MAPT (0.45) | MAPTBCHECYP2C19GUSBMAOB | |
| Potassium SCHEMBL30132698 | 0.97 | MAPT (0.44) | MAPTBCHECYP2C19GUSBMAOB | |
| SCHEMBL28421259 | 0.97 | MAPT (0.44) | MAPTBCHECYP2C19GUSBMAOB | |
| SCHEMBL28418761 | 0.97 | MAPT (0.44) | MAPTBCHECYP2C19GUSBMAOB | |
| SCHEMBL28098802 | 0.82 | CYP3A4 (0.48) | MAPTCYP2C19MAOBMAOAKMT2A | |
| SCHEMBL29561663 | 0.80 | MAPT (0.42) | MAPTBCHECYP2C19MAOBKMT2A | |
| SCHEMBL30573 | 0.80 | MAPT (0.42) | MAPTBCHECYP2C19MAOBKMT2A | |
| SCHEMBL28251467 | 0.80 | MAPT (0.42) | MAPTBCHECYP2C19MAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217690-B | Preparation method of propafenone hydrochloride and intermediate 2' -hydroxy dihydrochalcone thereof | 临沂大学（CN） | 2023-01-13 | — | — | CN | disclosed |