SCHEMBL30133232

SCHEMBL30133232

Cc1cc(-c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)nc(C)c1N

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 11/20 0.61
IKZF2 Q9UKS7 8/20 0.52
IKZF1 Q13422 1/20 0.49
CSNK1A1 P48729 2/20 0.48
GSPT1 P15170 1/20 0.46
DDB1 Q16531 1/20 0.46
IKZF3 Q9UKT9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23861066 1.00 CRBN (0.61) CRBNIKZF2IKZF1CSNK1A1GSPT1
SCHEMBL23860795 0.89 CRBN (0.61) CRBNIKZF2IKZF1CSNK1A1GSPT1
SCHEMBL26534442 0.89 CRBN (0.61) CRBNIKZF2IKZF1CSNK1A1GSPT1
SCHEMBL23860900 0.87 CRBN (0.64) CRBNIKZF2IKZF1CSNK1A1DDB1
SCHEMBL30133344 0.87 CRBN (0.64) CRBNIKZF2IKZF1CSNK1A1DDB1
SCHEMBL23861059 0.86 CRBN (0.62) CRBNIKZF2IKZF1CSNK1A1DDB1
SCHEMBL30133316 0.86 CRBN (0.62) CRBNIKZF2IKZF1CSNK1A1GSPT1
SCHEMBL30133272 0.86 CRBN (0.62) CRBNIKZF2IKZF1CSNK1A1DDB1
SCHEMBL23860995 0.86 CRBN (0.62) CRBNIKZF2IKZF1CSNK1A1GSPT1
SCHEMBL26534425 0.86 CRBN (0.62) CRBNIKZF2IKZF1CSNK1A1DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4126843-B1 SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER BRISTOL MYERS SQUIBB CO (US) 2026-02-11 EP claimed
CN-115605466-B Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司 2024-11-01 CN claimed
EP-4126843-A1 SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER Bristol-Myers Squibb Company (US) 2023-02-08 EP claimed
CN-115605466-A Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司(US) 2023-01-13 CN claimed
CN-115605466-B Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司 2024-11-01 CN disclosed
CN-115605466-A Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司(US) 2023-01-13 CN disclosed