SCHEMBL30133288

SCHEMBL30133288

O=C1CCC(N2Cc3cc(-c4cc(-c5ccccc5)c5ccccc5n4)ccc3C2=O)C(=O)N1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 9/20 0.57
IKZF1 Q13422 3/20 0.55
CSNK1A1 P48729 1/20 0.54
IKZF2 Q9UKS7 7/20 0.51
MAP1LC3B Q9GZQ8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23860946 1.00 CRBN (0.57) CRBNIKZF1CSNK1A1IKZF2MAP1LC3B
SCHEMBL30133309 0.91 CRBN (0.55) CRBNIKZF1CSNK1A1IKZF2
SCHEMBL30133320 0.91 CRBN (0.59) CRBNIKZF1CSNK1A1IKZF2MAP1LC3B
SCHEMBL30133283 0.91 CRBN (0.59) CRBNIKZF1CSNK1A1IKZF2
SCHEMBL23860951 0.91 CRBN (0.59) CRBNIKZF1CSNK1A1IKZF2
SCHEMBL23860989 0.91 CRBN (0.55) CRBNIKZF1CSNK1A1IKZF2
SCHEMBL23860923 0.91 CRBN (0.59) CRBNIKZF1CSNK1A1IKZF2MAP1LC3B
SCHEMBL23860881 0.88 CRBN (0.53) CRBNIKZF1CSNK1A1IKZF2
SCHEMBL30133303 0.88 CRBN (0.53) CRBNIKZF1CSNK1A1IKZF2
SCHEMBL23860821 0.87 CRBN (0.59) CRBNIKZF1CSNK1A1IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4126843-B1 SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER BRISTOL MYERS SQUIBB CO (US) 2026-02-11 EP claimed
CN-115605466-B Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司 2024-11-01 CN claimed
CN-115605466-A Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司(US) 2023-01-13 CN claimed
CN-115605466-B Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司 2024-11-01 CN disclosed
CN-115605466-A Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司(US) 2023-01-13 CN disclosed