Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.60 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.55 |
| ▸ | IKZF1 | Q13422 | 4/20 | 0.54 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | IL1B | P01584 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23860877 | 1.00 | CRBN (0.60) | CRBNCSNK1A1IKZF1IKZF2BRD4 | |
| SCHEMBL30133228 | 0.87 | CRBN (0.62) | CRBNCSNK1A1IKZF1IKZF2BRD4 | |
| SCHEMBL23860915 | 0.87 | CRBN (0.62) | CRBNCSNK1A1IKZF1IKZF2BRD4 | |
| SCHEMBL30133283 | 0.86 | CRBN (0.59) | CRBNCSNK1A1IKZF1IKZF2BRD4 | |
| SCHEMBL23860951 | 0.86 | CRBN (0.59) | CRBNCSNK1A1IKZF1IKZF2BRD4 | |
| SCHEMBL23860910 | 0.86 | CRBN (0.56) | CRBNCSNK1A1IKZF1IKZF2 | |
| SCHEMBL30133229 | 0.86 | CRBN (0.56) | CRBNCSNK1A1IKZF1IKZF2 | |
| SCHEMBL23861043 | 0.85 | CRBN (0.62) | CRBNCSNK1A1IKZF1IKZF2BRD4 | |
| SCHEMBL23860875 | 0.84 | CRBN (0.61) | CRBNCSNK1A1IKZF1IKZF2BRD4 | |
| SCHEMBL23860946 | 0.84 | CRBN (0.57) | CRBNCSNK1A1IKZF1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126843-B1 | SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER | BRISTOL MYERS SQUIBB CO (US) | 2026-02-11 | — | — | EP | claimed |
| CN-115605466-B | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-11-01 | — | — | CN | claimed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | claimed |
| CN-115605466-B | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-11-01 | — | — | CN | disclosed |
| EP-4126843-A1 | SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER | Bristol-Myers Squibb Company (US) | 2023-02-08 | — | — | EP | disclosed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | disclosed |