SCHEMBL30133345

SCHEMBL30133345

O=C1CCC(N2Cc3cc(-c4ccc5ccccc5n4)ccc3C2=O)C(=O)N1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 9/20 0.59
IKZF1 Q13422 2/20 0.54
IKZF2 Q9UKS7 9/20 0.53
CSNK1A1 P48729 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23860821 1.00 CRBN (0.59) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL23860868 0.89 CRBN (0.59) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL30133323 0.89 CRBN (0.59) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL23860862 0.88 CRBN (0.55) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL23860939 0.88 CRBN (0.69) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL30133268 0.88 CRBN (0.58) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL23861033 0.88 CRBN (0.55) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL23861074 0.88 CRBN (0.58) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL23861019 0.88 CRBN (0.55) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL30133312 0.88 CRBN (0.55) CRBNIKZF1IKZF2CSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4126843-B1 SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER BRISTOL MYERS SQUIBB CO (US) 2026-02-11 EP claimed
CN-115605466-B Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司 2024-11-01 CN claimed
CN-115605466-A Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司(US) 2023-01-13 CN claimed
EP-4612140-A1 NEK7 DEGRADERS AND METHODS OF USE THEREOF Captor Therapeutics S.A. (PL) 2025-09-10 EP disclosed
CN-115605466-B Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司 2024-11-01 CN disclosed
WO-2024096753-A1 NEK7 DEGRADERS AND METHODS OF USE THEREOF CAPTOR THERAPEUTICS S.A. (PL) 2024-05-10 WO disclosed
WO-2024094819-A1 NEK7 DEGRADERS AND METHODS OF USE THEREOF CAPTOR THERAPEUTICS S.A. (PL) 2024-05-10 WO disclosed
EP-4126843-A1 SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER Bristol-Myers Squibb Company (US) 2023-02-08 EP disclosed
CN-115605466-A Substituted oxoisoindoline compounds for the treatment of cancer 百时美施贵宝公司(US) 2023-01-13 CN disclosed