Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13728798 | 1.00 | CYP1A2 (0.46) | CYP1A2CYP2A6NR4A2DAOTSHR | |
| SCHEMBL13830337 | 0.81 | CYP1A2 (0.43) | CYP1A2CYP2A6NR4A2DAOTSHR | |
| SCHEMBL11792894 | 0.79 | CYP1A2 (0.50) | CYP1A2CYP2A6NR4A2TSHRLMNA | |
| SCHEMBL30676607 | 0.76 | NR4A2 (0.51) | CYP1A2CYP2A6NR4A2KDM4ELMNA | |
| SCHEMBL29122464 | 0.76 | NR4A2 (0.51) | CYP1A2CYP2A6NR4A2KDM4ELMNA | |
| SCHEMBL7882102 | 0.75 | TRPM4 (0.45) | CYP1A2CYP2A6KDM4ELMNAMAPT | |
| SCHEMBL2749744 | 0.71 | CYP1A2 (0.43) | CYP1A2CYP2A6NR4A2DAOTSHR | |
| SCHEMBL30601891 | 0.71 | NR4A2 (0.46) | CYP1A2CYP2A6NR4A2TSHRKDM4E | |
| SCHEMBL11403030 | 0.71 | NR4A2 (0.46) | CYP1A2CYP2A6NR4A2TSHRKDM4E | |
| SCHEMBL13731201 | 0.68 | MAPT (0.40) | CYP1A2CYP2A6NR4A2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605466-B | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-11-01 | — | — | CN | disclosed |
| EP-4126843-A1 | SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER | Bristol-Myers Squibb Company (US) | 2023-02-08 | — | — | EP | disclosed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | disclosed |